Poly-L-Aspartic Acid Sodium Salt is a biodegradable polyanionic alternative for polymers and detergents. It can be used as modifier or additive use in situ strategy to encapsulate antibiotics in a bio-inspired CaCO3 structure enabling pH-sensitive drug release apt for therapeutic and imaging applications. It can also be used in biological study and technical or engineered material use of biomimetic mineralization of woven bone-like nanocomposites by using crosslinked collagen.