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Nicergoline
产品基本信息
产品编号:N394550
产品名称:Nicergoline
产品CAS:27848-84-6
规格含量:100mg
产品价格:面议
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产品详细介绍
标准品编号: N394550
名称: Nicergoline
别名: 1,6-Dimethyl-8β-(5-bromonicotinoyloxymethyl)-10α-methoxyergoline; Cergodum; Circo-Maren; Dilasenil; Duracebrol; Ergobel; Ergotop; FI 6714; MNE; Memoq; NSC 150531; Nicergolent; Nicotergoline; Sermion; TA 079; Vasospan; ((6aR,9R,10aS)-10a-Methoxy-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-Bromonicotinate; (8β)-10-Methoxy-1,6-dimethylergoline-8-methanol 5-Bromo-3-pyridinecarboxylate (ester); 5-Bromo-(10-methoxy-1,6-dimethylergolin-8β-yl)methyl Ester Nicotinic Acid
CAS号: 27848-84-6
分子式: C₂₄H₂₆BrN₃O₃
外观: 白色固体
熔点: 132-134°C
分子量: 484.39
储存: 冰箱
溶解度: DMSO, Methanol
种类: Research Tools; Pharmaceutical/API Drug Impurities/Metabolites; Lysergic Acid Derivatives; Tryptamines;
应用: Nicergoline is a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia. Nicergoline has shown to protect cultured neurons against β-amyloid toxicity. Nicergoline protects against neuronal cell death induced by activated microglia and astrocytes through the inhibition of inflammatory mediators and the upregulation of neurotrophic factors by glial cells. Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.
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