Abiaterone-5,6-epoxide__A108535_【莱耀标准品网】

产品基本信息

产品编号：A108535

产品名称：Abiaterone-5,6-epoxide

产品CAS：

规格含量：2mg

产品价格：面议

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产品详细介绍

标准品编号:	A108535
名称:	Abiaterone-5,6-epoxide
别名:	5,6-Epoxy Abiaterone
分子式:	C₂₄H₃₃NO₂
分子量:	367.52
类别:	Standards; Steroids;
应用:	Abiaterone-5,6-Epoxide is an impurity of Abiraterone (A108490), which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
参考:	Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)

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