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产品编号:A609515
产品名称:N-[2-Aminoethyl] Pomalidomide Trifluoroacetic Acid Salt
产品CAS:1957235-67-4
规格含量:10mg
产品价格:面议
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产品详细介绍
标准品编号:
A609515
名称:
N-[2-Aminoethyl] Pomalidomide Trifluoroacetic Acid Salt
别名:
4-((2-Aminoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Trifluoroacetic Acid Salt;
CAS号:
1957235-67-4
备用CAS:
Free Base: 1130688-12-8/ Chiral:1130688-13-9
分子式:
C₁₅H₁₆N₄O₄ • x(C ₂HF₃O₂)
状态:
Light Orange to Yellow Solid
熔点:
>224°C (dec.)
分子量:
316.3111402
储存:
Hygroscopic, 冰箱保存, under inert atmosphere
溶解性:
DMSO (Slightly), Methanol (Slightly)
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
N-[2-Aminoethyl] Pomalidomide Trifluoroacetic Acid Salt is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
参考:
Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)