Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)-4-nitroisoindoline-1,3-dione-d2 is an intermediate for the synthesis of Pomalidomide-(d4 major) (P688202), which is the labeled analogue of Pomalidomide (P688200), a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.