(Z)-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic Acid; Sulindac Related Compound C
CAS号:
49627-27-2
参考CAS号:
EZ undefined: 32004-67-4
分子式:
C₂₀H₁₇FO₂S
外观:
Yellow to Orange Solid
熔点:
177-182°C
分子量:
340.41
储存:
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Very Slightly, Heated)
稳定性:
Hygroscopic
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP.
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