Aconitine

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产品编号:A189875

产品规格:10mg

产品价格:面议


产品详情

标准品编号: A189875
名称: Aconitine
别名: (1α,3α,6α,14α,15α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol 8-Acetate 14-Benzoate;
CAS号: 302-27-2
分子式: C₃₄H₄₇NO₁₁
状态: 白色固体
熔点: >180ºC (dec.)
分子量: 645.74
储存: 冰箱保存
溶解性: Chloroform (Slightly), Ethyl Acetate (Slightly, Sonicated)
类别: Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用: Neurotoxin. Activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction. Aconitine also blocks norepinephrine reuptake. In the heart, aconitine induces ventricular tachycardia after intracoronary injection. In cultured ventricular myocytes, aconitine increases the duration of the action potential and induces the appearance of early after depolarization. Used in producing heart arrhythmia in experimental animals.
危险品信息: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
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