产品编号：A426903
产品规格：10mg
产品价格：面议
| 标准品编号: | A426903 |
| 名称: | Agmatine Sulfate-15N2, 13C |
| 别名: | N-(4-aminobutyl)guanidine Sulfate-15N2, 13C; NIH 11035 -15N2, 13C |
| 备用CAS: | 未标记：2482-00-0 |
| 分子式: | C₄¹³CH₁₆N₂¹⁵N₂O₄S |
| 分子量: | 231.25 |
| 类别: | Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | General Uses: Neuroprotective, CNS studies, Autism and depression research Description: Agmatine Sulfate-15N2, 13C is a labeled analogue of Agmatine Sulfate (A426900), a polyamine derived from L-arginine (A769500) decarboxylation and is a known putative endogenous neurotransmitter at imidazoline receptors. Agmatine sulfate displaces clonidine at α2-adrenergic and at imidazoline receptors and was recently shown to exert some neuroprotective effects. It blocks NMDVIP(LA)receptor associated cation channels. Acts as a competitive inhibitor of nitric oxide synthase (NOS). It functions as neurotransmitter since it is stored in synaptic vesicles and is related from axon terminals by depolarization(1). Protects autistic behavior in rats (2) and reverses depressive like behavior in mice. (3) |
| 参考: |
|
