产品编号：A601540
产品规格：250mg
产品价格：面议
| 标准品编号: | A601540 |
| 名称: | (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride |
| 别名: | (αR,γS)-γ-Amino-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid Ethyl Ester Hydrochloride; [S-(R*,S*)]-γ-Amino-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid Ethyl Ester Hydrochloride; Ethyl (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpentanoate Hydrochloride |
| CAS号: | 149690-12-0 |
| 备用CAS: | Free base: 752174-62-2 |
| 分子式: | C₂₀H₂₆ClNO₂ |
| 状态： | 白色至白色固体 |
| 熔点： | 155 - 162°C |
| 分子量: | 347.88 |
| 储存： | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解性: | DMSO (Slightly), Methanol (Slightly) |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines; |
| 应用: | (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is used as a reagent in the synthesis of LCZ696, an angiotensin II receptor and neprilysin receptor dual inhibitor. (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is also used as a reagent in the preparation of novel NEP inhibitor prodrugs for the treatment of hypertension and cardiovascular diseases. |
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