产品编号：A602165

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	A602165
名称:	5-Amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro-3H-1,2,4-Triazol-3-one
CAS号:	1847413-14-2
分子式:	C₁₅H₁₄N₄O
分子量:	266.3
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	5-Amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro-3H-1,2,4-Triazol-3-one is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout.
参考:	Burns, C., et al.: Lancet 377, 165 (2011); Miner, J. et al.: PCT Int. Appl. WOÂ2011159732ÂA1Â20111222 (2011);ÂCrittenden, D. B. et al.: Clinical InvestigationÂ1,Â1563-1575 (2011)