产品编号：A612095

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	A612095
名称:	4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide
别名:	MS 436;
CAS号:	1395084-25-9
分子式:	C₁₈H₁₇N₅O₃S
分子量:	383.42
类别:	Research Tools;
应用:	MS 436 is a potent bromodomain inhibitor, binding to BRD4 and more tightly to subdomain BD1 than BD2. These domains play a key role in inflammatory gene expression, mitosis and viral/host interaction. Applications involving innhibition of bromodomains include decrease in cell proliferation for leukemia and destruction of tumor cells.
参考:	Gallenkamp, D. et al.: ChemMedChem, 9, 438 (2014); Zhang, G. et al.: J. med. Chem., 56, 9251 (2013);