产品编号：A790545

产品规格：10mg

产品价格：面议

---

产品详情

标准品编号:	A790545
名称:	AT 101
别名:	(-)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; (R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; (2R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde; (-)-Gossypol; (R)-(-)-Gossypol; (R)-Gossypol
CAS号:	90141-22-3
分子式:	C₃₀H₃₀O₈
分子量:	518.56
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	AT 101 shows significant inhibitory activities against HIV-1 replication, HIV-1 mediated cell-cell fusion and HIV gp41 6-helix bundle formation, with gp41 as its main target. AT 101 is also a known potent inhibitor of anti-apoptotic Bcl-2 proteins.
文献	Yang, J.; et al.: Bioorganic Med. Chem. Lett., 28, 49 (2018); Wang, G.; et al.: J. Med. Chem., 49, 6139 (2006)