产品编号：B288545

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	B288545
名称:	(R)-7-Benzyloxy Warfarin Quinidine Salt
别名:	(R)-7-(Benzyloxy)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one (S)-(6-Methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol (1:1)
备用CAS:	56-54-2 and 30992-69-9
分子式:	C₄₆H₄₆N₂O₇
分子量:	738.87
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(R)-7-Benzyloxy Warfarin Quinidine Salt is the starting material used in the synthesis of 7-Hydroxy Warfarin (H996130), a metabolite of Warfarin (W498500), a coumarin anticoagulant. Marketed as the racemate; the S-(-)-form is the more potent isomer. Anticoagulant.
文献	Barbato, F., et al.: J. Pharm. Sci., 86, 225 (1997); Kavana, M., et al.: Biochemistry, 42, 10238 (2003); Franco, A., et al.: Environ. Toxicol. Chem., 28, 458 (2009); Hagan, E.C., et al.: J. Am. Pharm. Assoc. Sci. Ed., 42, 379 (1953); Bell, R.G., et al.: Biochemistry, 11, 1959 (1972); Valente, J.E., et al.: J. Med. Chem., 20, 1489 (1977); Back, N., et al.: Pharmacol. Res. Commun., 10, 445, (1978); Babhair, S.A., et al.: Anal. Profiles Drug Subs., 14, 423 (1985); Takahashi, H., et al.: Echizen, Clin. Pharmacokinet., 40, 587 (2001)