产品编号：B330240

产品规格：5g

产品价格：面议

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产品详情

标准品编号:	B330240
名称:	Betulin
别名:	Lup-20(29)-ene-3β,28-diol; Lup-20(30)-ene-3β,28-diol; 3aH-Cyclopenta[a]chrysene, lup-20(29)-ene-3,28-diol deriv.; (+)-Betulin; 3,28-Dihydroxy-lupeol; 3β,28-Dihydroxylup-20(29)-ene; Betulin; Betuline; Betulinic alcohol; Betulinol; Betulol; NSC 4644; Trochol
CAS号:	473-98-3
分子式:	C₃₀H₅₀O₂
外观：	Pale Brown to Beige Solid
熔点:	>250°C (dec.)
分子量:	442.72
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	Chloroform (Slightly), Methanol (Slightly, Heated)
稳定性:	Hygroscopic
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Betulin is a derivative of Betulinic Acid (B330250), used in the treatment of cancer and HIV disease. Betulinic Acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity
文献	Cichewicz, R. et al.: Med. Res. Rev., 24, 90 (2003); Pisha, E. et al.: Nat. Med., 1, 1046 (1995); Fulda, S. et al.: Cancer Res., 57, 4956 (1997); Kashiwada, Y. et al.: J. Med. Chem., 39, 1016 (1996); Genet, C. et al.: J. Med. Chem., 53, 178 (2010);

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