产品编号：B592530
产品规格：50mg
产品价格：面议
| 标准品编号: | B592530 |
| 名称: | (R)-(+)-Blebbistatin O-Benzoate |
| 别名: | (R)-3a-(Benzoyloxy)-1,2,3,3a-tetrahydro-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one; |
| CAS号: | 1217635-67-0 |
| 分子式: | C₂₅H₂₀N₂O₃ |
| 外观: | Orange Solid |
| 熔点: | 157-159°C |
| 分子量: | 396.44 |
| 储存: | 冰箱保存 |
| 溶解度: | Chloroform, Methanol |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | (R)-(+)-Blebbistatin O-Benzoate is a derivative of Blebbistatin (B592495). (R)-(+)-Blebbistatin is a 1-phenyl-2-pyrrolidinone derivative and a selective inhibitor of non-muscle myosin II (1, 2, 3). It blocks cell blebbing rapidly and reversibly and also disrupts directed cell migration and cytokinesis in vertebrate cell. (R)-(+)-Blebbistatin can also inhibit contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. (R)-(+)-Blebbistatin is suitable as a negative control for (S)-(-)-Blebblastatin. |
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