产品编号：B662030

产品规格：5g

产品价格：面议

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产品详情

标准品编号:	B662030
名称:	N-Boc-piperazine-5,5-dimethylhydantoin
别名:	t-Butyl 4-((4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)methyl)piperazine-1-carboxylate
分子式:	C₁₅H₂₆N₄O₄
外观:	White Crystalline Solid
分子量:	326.39
溶解度:	Chloroform, Methanol
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-Boc-piperazine-5,5-dimethylhydantoin is an intermediate in synthesizing 3-Piperazinylmethyl-5,5-dimethylhydantoin Dihydrochloride (D473640), a derivative of 5,5-Dimethylhydantoin (D473300). 3-Piperazinylmethyl-5,5-dimethylhydantoin is also part of a group of small molecules that have the ability to reversibly inhibit Protein Arginine Deiminase (PAD4), which can potentially be used to treat inflammatory bowel disease and cancer.
参考文献	Chumanevich, A., et al.: Am. J. Physiol-Endoc. M., 300, G929 (2011); Wang, Y., et al.: J. Biol. Chem., 287, 25941 (2012); Wei, L., et al.: J. Med. Chem., 56, 1715 (2013)