产品编号：B689145

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	B689145
名称:	2-[[5-Bromo-4-(5-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid
别名:	2-[[5-Bromo-4-(5-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid
CAS号:	1533519-97-9
分子式:	C₁₇H₁₄BrN₃O₂S
分子量:	404.28
类别:	Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-[[5-Bromo-4-(5-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout.
参考文献	Burns, C., et al.: Lancet 377, 165 (2011); Miner, J. et al.: PCT Int. Appl. WOÂ2011159732ÂA1Â20111222 (2011);ÂCrittenden, D. B. et al.: Clinical InvestigationÂ1,Â1563-1575 (2011)