产品编号：B692540

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	B692540
名称:	(1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol
别名:	trans-4-[[2-(Butylamino)-5-[5-(4-morpholinylmethyl)-2-pyridinyl]-4-pyrimidinyl]amino]cyclohexanol; UNC2250
CAS号:	1493694-70-4
分子式:	C₂₄H₃₆N₆O₂
外观:	淡黄色固体
熔点:	207-210ºC
分子量:	440.58
储存:	冰箱保存, under inert atmosphere
溶解度:	Chloroform (Slightly, Heated), Ethyl Acetate (Slightly, Heated), Methanol (Sligh
类别:	Research Tools; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol inhibits steady-state phosphorylation of endogenous Mer and blocks ligand-stimulated activation of a chimeric EGFR-Mer protein. (1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol also decreases colony-forming potential in rhabdoid and NSCLC tumor cells.
参考文献	Zhang, W., et. al.: J. Med. Chem., 56, 9683 (2013)