产品编号：B695605

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	B695605
名称:	BMS 961
别名:	3-Fluoro-4-[[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-2-naphthalenyl)acetyl]amino]-benzoic Acid;
CAS号:	185629-22-5
分子式:	C₂₃H₂₆FNO₄
分子量:	399.46
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	BMS961 is a potent and selective retinoic acid receptor gamma (RARγ) agonist with IC50 values of 30 nM. RARγ belongs to the family of nuclear receptors which regulates transcription. in vitro, application of BMS961on mouse ear skin was found to cause a significant increase of thymic stromal lymphopoietin (TSLP) transcripts1.
参考文献	Abu-Abed, et al.: J.Biol.Chem. 273 2409, (1998); Taneja et al.: Proc.Natl.Acad.Sci.USA 93 6197 (1996); Klaholz, et al.: Proc.Natl.Acad.Sci. 97 6322 (2000);