产品编号：B809820

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	B809820
名称:	(2R,4S)-4-((t-Butoxycarbonyl)amino)-1,2-dihydroxy-2,6-dimethyl-3-oxohepan-4-tyl
别名:	N-[(1S,3R)-3,4-Dihydroxy-3-methyl-1-(2-methylpropyl)-2-oxobutyl]-carbamic Acid 1,1-Dimethylethyl Ester;
CAS号:	1541172-78-4
分子式:	C₁₄H₂₇NO₅
分子量:	289.37
类别:	Standards;
应用:	(2R,4S)-4-((t-Butoxycarbonyl)amino)-1,2-dihydroxy-2,6-dimethyl-3-oxohepan-4-tyl is an intermediate used in the synthesis of Carfilzomib (2S,4S)-Diol (C183495), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
参考文献	Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);