产品编号：B943078

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	B943078
名称:	tert-Butyl (1-Hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)carbamate
别名:	1,1-Dimethylethyl Ester [1,​1-​bis(hydroxymethyl)​-​3-​(4-​octylphenyl)​propyl]​carbamic Acid
CAS号:	844496-96-4
分子式:	C₂₄H₄₁NO₄
分子量:	407.59
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	tert-Butyl (1-Hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)carbamate is the intermediate in the synthesis of Mono-O-acetyl Fingolimod TFA (F524600), which is an impurity of Fingolimod (F805000, HCl salt) which is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs.
参考文献	Brinkmann, V., et al.: Transplantation, 72, 764 (2001). Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002). Mtaloubian, M., et al.: Nature, 427, 355 (2004)