产品编号：C175240

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	C175240
名称:	Canagliflozin L-Glucitol
别名:	(2R,3S,4S,5R,6S)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;
分子式:	C₂₄H₂₅FO₅S
分子量:	444.52
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Canagliflozin L-Glucitol is a metabolite of Canagliflozin (C175190) a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
参考文献	Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);