产品编号：C177625

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	C177625
名称:	1-[[[(1R)-1-[3-[(2S,R)-2-[[(1-Carboxycyclopropyl)methyl]thio]-2-(7-chloro-2-quinolinyl)ethyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methylcyclopropaneacetic Acid
别名:	Montelukast Impurity;
分子式:	C₄₁H₄₆ClNO₅S₂
分子量:	732.39
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1-[[[(1R)-1-[3-[(2S,R)-2-[[(1-Carboxycyclopropyl)methyl]thio]-2-(7-chloro-2-quinolinyl)ethyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methylcyclopropaneacetic Acid is derived from Montelukast Methyl Ester (M568080), which is an impurity of the antiasthmatic drug Montelukast (M568000), a selective leukotriene D4-receptor antagonist. Used as an anti-asthmatic.
参考文献	Balani, S., et al.: Drug Metab. Dispos., 25, 1282 (1997); Radhakrishna, T., et al.: Pharm. Biomed. Anal., 31, 359 (2003); Nelson, E., et al.: J. Pharm. Sci., 95, 1527 (2006); Labelle, M., et al.: Bioorg. Med. Chem. Lett., 5, 283 (1995), Jones, T.R., et al.: Can. J. Physiol. Pharmacol., 73, 191 (1995), Markham, A. and Faulds, D.: Drugs, 56, 251 (1998)