产品编号：C227660

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	C227660
名称:	N-Cbz-5-hydroxy-6-oxo-N-(2,4,6-trifluorobenzyl)-1,6-dihydropyrimidine-4-carboxamide
分子式:	C₂₁H₁₇F₃N₄O₅
外观:	Grey Solid
分子量:	462.38
溶解度:	DMF; Methanol (Partial)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-Cbz-5-hydroxy-6-oxo-N-(2,4,6-trifluorobenzyl)-1,6-dihydropyrimidine-4-carboxamide is an intermediate used in the synthesis of N-((5-Hydroxy-6-oxo-4-((2,4,6-trifluorobenzyl)carbamoyl)-1,6-dihydropyrimidin-2-yl)methyl)-1,3,4-oxadiazole-2-carboxamide (H950690), which is a derivative of Raltegravir (R100305), a potent integrase (IN) inhibitor for WT and S217Q PFV IN.
参考文献	Hare, S., et al.: Proc. Natl. Acad. Sci. U. S. A., 107, 20057 (2010); Hicks, C., et al.: Clin. Infect. Dis., 48, 931 (2009); Moss, D., et al.: Antimicrob. Agents Chemother., 56, 3020 (2012); Hare, S., et al.: Mol. Pharmacol., 80, 565 (2011)