产品编号：C292150
产品规格：100mg
产品价格：面议
| 标准品编号: | C292150 |
| 名称: | CHIR-99021 Hydrochloride |
| 别名: | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile Hydrochloride; CHIR 911 Hydrochloride; CT 99021 Hydrochloride; |
| CAS号: | 1797989-42-4 |
| 参考CAS: | Free Base: 252917-06-9 |
| 分子式: | C₂₂H₁₉Cl₃N₈ |
| 外观: | 灰白色至浅褐色固体 |
| 熔点: | >238°C (dec.) |
| 分子量: | 501.8 |
| 储存: | Hygroscopic, 冰箱保存, Under Inert Atmosphere |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | CHIR-99021 is a potent and highly selective inhibitor of glycogen synthase kinase 3 (GSK-3). CHIR-99021 activates glycogen synthesis in CHO-IR cells and in isolated type 1 diabetic rat skeletal muscle. CHIR-99021 has also been shown to induce the reprogramming of murine and human somatic cells into stem cells. |
| 参考文献 | |
