产品编号：C363660

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	C363660
名称:	α-Chloroethyl Phenyl Sulfoxide
别名:	[(1-Chloroethyl)sulfinyl]-benzene; 1-Chloroethyl Phenyl Sulfoxide; [(1-Chloroethyl)sulfinyl]benzene;
CAS号:	26910-40-7
分子式:	C₈H₉ClOS
外观:	Light Yellow Oil
分子量:	188.67
溶解度:	Dichloromethane, Ethyl Acetate, Methanol
类别:	Building Blocks; Miscellaneous;
应用:	α-Chloroethyl Phenyl Sulfoxide is an intermediate in synthesizing 3-Deoxy-3-acetylabiraterone-3-ene (D232060), which is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
参考文献	Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005);