产品编号：C367395

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	C367395
名称:	3-Chloroindomethacin
别名:	[1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic Acid; 1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-acetic Acid; Indomethacin Impurity G; Indomethacin EP Impurity G
杂质:	Indomethacin EP Impurity G
CAS号:	402849-26-7
分子式:	C₁₉H₁₅Cl₂NO₄
分子量:	392.23
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-Chloroindomethacin (Indomethacin EP Impurity G) is an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO).
参考文献	Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)