产品编号：C377830

产品规格：10g

产品价格：面议

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产品详情

标准品编号:	C377830
名称:	5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxylic Acid
别名:	1-(2,4-Dichlorophenyl)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic Acid; 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic Acid;
CAS号:	162758-35-2
分子式:	C₁₇H₁₁Cl₃N₂O₂
外观:	白色固体
熔点:	214-217°C
分子量:	381.64
储存:	冰箱保存
溶解度:	DMSO (Slightly), Methanol (Slightly, Heated)
类别:	Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxylic Acid is used in the preparation of biarylpyrazole based derivatives as cannabinoid CB1 receptor antagonists. It is metabolite M9 of Rimonabant (R517800), an antiobesity agent.
参考文献	Kang, S.Y. et al.: Bioorg. Med. Chem. Lett., 18, 2385 (2008); Fulp, A. et al.: Bioorg. Med. Chem. Lett., 21, 5711 (2011); Bergstrom, M.A. et al.: Drug Metab. and Dispos., 39, 1823 (2011);