产品编号：C378110

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	C378110
名称:	2-[(2-Chlorophenyl)-β-hydroxy-methyl]-4-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester
别名:	Ethyl 2-((2-Chlorophenyl)(hydroxy)methyl)-4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate
分子式:	C₂₃H₂₂ClNO₇
分子量:	459.88
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-[(2-Chlorophenyl)-β-hydroxy-methyl]-4-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester is an intermediate in the synthesis of Amlodipine Besilate (A633500); a dihydropyridine calcium channel blocker which is also used as an antianginal and antihypertensive.
参考文献	Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc Pharmacol., 9, 110 (1987); Packer, M., et al.: N. Engl. J. Med., 335, 1107 (1996)