产品编号：C380158

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	C380158
名称:	(RS, SR) 3-[[2-(4-Chlorophenyl)-2-cyclopentyl-2-hydroxyacetyl]oxy]-1,1-dimethylpyrrolidinium Bromide
别名:	Glycopyrrolate Impurity
杂质名:	Glycopyrrolate
分子式:	C₁₉H₂₇BrClNO₃
分子量:	432.78
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(RS, SR) 3-[[2-(4-Chlorophenyl)-2-cyclopentyl-2-hydroxyacetyl]oxy]-1,1-dimethylpyrrolidinium Bromide is a mixture of (R)-3-((S)-2-(4-Chlorophenyl)-2-cyclopentyl-2-hydroxyacetoxy)-1,1-dimethylpyrrolidin-1-ium Bromide (C427775) and (S)-3-((R)-2-(4-Chlorophenyl)-2-cyclopentyl-2-hydroxyacetoxy)-1,1-dimethylpyrrolidin-1-ium Bromide (C427710). (RS, SR) 3-[[2-(4-Chlorophenyl)-2-cyclopentyl-2-hydroxyacetyl]oxy]-1,1-dimethylpyrrolidinium Bromide is a Glycopyrronium Bromide (G656980) impurity, which has a broad pharmacology and medical applications. Glycopyrronium blocks muscarinic receptors, thus inhibiting cholinergic transmission. It is also used to reduce excessive saliva (sialorrhea). It also decreases acid secretion in the stomach and so may be used for treating stomach ulcers, in combination
参考文献	Haddad E.B., et al.: Br. J. Pharma., 127, 413 (1999); Bajaj, V., et al.: Br. J. Dermatol., 157, 118 (2007); Miler, RJ., et al.: Arch. Pediatr. Adolesc. Med., 154, 1214 (2000); Kaltiala, E., et al.: J. Pharm. Pharmacol., 26, 352 (1974), Kongsrud, F., et al.: Acta Anaesthesiol. Scand., 26, 620 (1982)