产品编号：C441115

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	C441115
名称:	1S,2S-Cilastatin Hydrochloride
别名:	[S-[R*,R*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-Heptenoic Acid Hydrochloride;
参考CAS:	Free Base: 107873-05-2
分子式:	C₁₆H₂₆N₂O₅S • (HCl)
分子量:	358.453646
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1S,2S-Cilastatin Hydrochloride is a diastereoisomer of Cilastatin (C441100), which prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition.
参考文献	Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983); Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983); Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983);