产品编号：C988610

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	C988610
名称:	(3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt
别名:	ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt
CAS号:	254452-88-5
参考CAS:	Free Acid: 254452-86-3
分子式:	C₂₅H₂₄FNO₄ •1/2Ca
外观:	白色固体
熔点:	>187°C (dec.)
分子量:	440.49
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly)
类别:	Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt is the 3S,5R- Isomer of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent.
参考文献	Suzukim M., et al.: Bioorg. Med. Chem., 9, 2977 (1999); Yen, H., et al.: J. Clin. Invest., 98, 1253 (1996); Zou, Y., et al.: J. Biol. Chem., 274, 9760 (1999); Sun, X., et al.: Cancer Res., et al.: 61, 3382 (2001); Ladas, E.J., et al.: Clin. Oncol., 22, 517 (2004);