产品编号：D243850

产品规格：1g

产品价格：面议

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产品详情

标准品编号:	D243850
名称:	2-Deoxy-D-erythro-pentofuranose 5-(4-Methylbenzoate)
参考CAS号:	α-OH: 502633-91-2/ Aldehyde form: 1195620-56-4
分子式:	C₁₃H₁₆O₅
分子量:	252.26
种类:	Research Tools;
应用:	2-Deoxy-D-erythro-pentofuranose 5-(4-methylbenzoate) is an impurity of Decitabine (α-isomer: D226730), a DNA hypomethylating agent that is used to treat various forms of cancer, such as myelogeneous leukemia and metastatic lung cancerBy inhibiting DNA methyltransferase, Decitabine silences the tumour suppressor genes and, consequently, “normalizing” gene expression in cancerous cells.
参考文献	Aribi, A., et al.: Cancer, 109, 713 (2007); Issa, J., et al.: Blood, 103, 1635 (2004); Kantarjian , H., et al.: Cancer, 98, 522 (2003); Momparler, R., et al.: Anti-Cancer Drug., 8, 358 (1997); Plimack, E., et al.: Leukemia Lymphoma, 48, 1472 (2007)