产品编号：D282085

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	D282085
名称:	Desamino Hydroxy Lenvatinib
别名:	4-(3-Chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxylic Acid
CAS号:	417717-21-6
分子式:	C₂₁H₁₈ClN₃O₅
分子量:	427.84
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Desamino Hydroxy Lenvatinib serves as a reagent for the synthesis of urea derivatives containing nitrogenous aromatic ring compounds that functions as angiogenesis inhibitors for treatment of diseases. It is also a derivative compound of Lenvatinib (L329400) that serves as orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.
参考文献	Funahashi, Y., et al.: PCT Int. Appl.Â(2002),ÂWOÂ2002032872ÂA1Â20020425; Matsui, J., et al.: Clin. Cancer Res., 14, 5459 (2008); Gild, M., et al.: Nature Rev. Endocrinol., 7, 617 (2011)