产品编号：D290988

产品规格：5mg

产品价格：面议

---

产品详情

标准品编号:	D290988
名称:	Deschloro Lapatinib
别名:	N-[4-[(3-Fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine;
CAS号:	633370-23-7
分子式:	C₂₉H₂₇FN₄O₄S
分子量:	546.61
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Deschloro Lapatinib is dechlorinated analogue of drug Lapatinib (L175808), which is a selective inhibitor of epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinases. Lapatinib is used to treat breast cancer, especially metastatic breast cancer that has progressed after trastuzumab treatment and other chemotherapy.
参考文献	Konecny, G., et al.: Cancer Res., 66, 1630 (2006); Geyer, C., et al.: N. Engl. J. Med., 355, 2733 (2006);