Di-(tert-Butyl-dimethylsilyl) Curcumin

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产品编号:D428050

产品规格:250mg

产品价格:面议


产品详情

标准品编号: D428050
名称: Di-(tert-Butyl-dimethylsilyl) Curcumin
别名: (1E,4Z,6E)-1,7-Bis[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-5-hydroxy-1,4,6-heptatrien-3-one
CAS号: 1134639-23-8
分子式: C₃₃H₄₈O₆Si₂
外观: Yellow Solid
熔点: 138-140ºC
分子量: 596.9
储存: 冰箱保存
溶解性: Chloroform (Slightly), Methanol (Slightly)
种类: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: Protected Curcumin (C838500). A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
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