产品编号：D447825

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	D447825
名称:	GNE-781
别名:	3-[7-(Difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-5H-pyrazolo[4,3-c]pyridine-5-carboxamide
CAS号:	1936422-33-1
分子式:	C₂₇H₃₃F₂N₇O₂
外观:	白色至淡黄色固体
熔点:	135-140oC
分子量:	525.59
储存:	冰箱保存
溶解性:	DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	GNE-781 is a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein, binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.
参考文献	Romero, F.A.; et al.: J. Med. Chem, DOI: 10.1021/acs.jmedchem.7b00796 (2017)