产品编号：D450535

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D450535
名称:	Saxagliptin Lactose Adduct
别名:	;Saxagliptin impurity; (1R,3R,5R)-2-((2R)-2-(((3R,4R,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((3R,4S,5R,6S)-3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)-2-((1r,3S,5R,7S)-3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile
分子式:	C₂₉H₄₃N₃O₁₂
分子量:	625.66
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Saxagliptin Lactose Adduct is a lactose adduct of Saxagliptin, which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
参考文献	Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),