产品编号：D454465

产品规格：100mg

产品价格：面议

---

产品详情

标准品编号:	D454465
名称:	[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate
别名:	Quercetin Pentaacetate; 3,5,7-Tris(acetyloxy)-2-[3,4-bis(acetyloxy)phenyl]-4H-1-benzopyran-4-one
CAS号:	1064-06-8
分子式:	C₂₅H₂₀O₁₂
外观:	Beige Solid
分子量:	512.42
溶解性:	Dichloromethane, Ethyl Acetate
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	[5,7-Diacetyloxy-2-(3,4-diacetyloxyphenyl)-4-oxochromen-3-yl] Acetate is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.
参考文献	Graziani, Y. et al.: J. Biochem., 135, 583 (1983); Levy, J. et al.: Biochem. Biophys. Res. Comm., 123, 1227 (1984); Wei, Y.Q. et al.: Cancer Res., 54, 4952 (1994);