产品编号：D455700
产品规格：1g
产品价格：面议
| 标准品编号: | D455700 |
| 名称: | Di-O-glycinoylcurcumin Dihydrochloride |
| 别名: | ((1E,6E)-3,5-Dioxohepta-1,6-diene-1,7-diyl)bis(2-methoxy-4,1-phenylene) bis(2-aminoacetate) Dihydrochloride |
| CAS号: | 1322544-82-0 |
| 参考CAS号: | Free Base: 357400-04-5 |
| 分子式: | C₂₅H₂₈Cl₂N₂O₈ |
| 外观: | Yellow Solid |
| 熔点: | >127ºC (dec.) |
| 分子量: | 555.4 |
| 储存: | Amber Vial, -20°C Freezer, Under inert atmosphere |
| 溶解性: | DMSO (Slightly), Methanol (Slightly) |
| 种类: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Di-O-glycinoylcurcumin Dihydrochloride is a metabolite of curcumin (C838500), which is a natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and antioxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. Curcumin is currently being examined as a possible therapeutic for the treatment of Alzheimers dise |
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