产品编号：D461585

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	D461585
名称:	(2S)​-1-​[2-​[(2R,​3R,​6S)​-​6-​[(2S,​3E,​5E,​7E,​9S,​11R)​-​2,​13-​Dimethoxy-​3,​9,​11-​trimethyl-​12-​oxo-​3,​5,​7-​tridecatrien-​1-​yl]​tetrahydro-​2-​hydroxy-​3-​methyl-​2H-​pyran-​2-​yl]​-​2-​oxoacetyl]​-​2-
别名:	(2S)-1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-Dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-2-piperidinecarboxylic Acid; [2R-[2α,2(S*),3α,6β(2S*,3E,5E,7E,9S*,11R*)]]-1-[[6-(2,13-Dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl)tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-2-piperidinecarboxylic Acid
CAS号:	147438-30-0
分子式:	C₃₂H₄₉NO₉
分子量:	591.73
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(2S)​-1-​[2-​[(2R,​3R,​6S)​-​6-​[(2S,​3E,​5E,​7E,​9S,​11R)​-​2,​13-​Dimethoxy-​3,​9,​11-​trimethyl-​12-​oxo-​3,​5,​7-​tridecatrien-​1-​yl]​tetrahydro-​2-​hydroxy-​3-​methyl-​2H-​pyran-​2-​yl]​-​2-​oxoacetyl]​-​2-​piperidinecarboxylic Acid is an impurity of Sirolimus (R124000) which is an immunosuppressant drug used to prevent rejection in organ transplantation.
参考文献	Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004)