产品编号：D469450

产品规格：1g

产品价格：面议

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产品详情

标准品编号:	D469450
名称:	(5R)-5-[(1S)-1-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-phenylethyl]tetrahydro-2-oxo-3-furancarboxylic Acid Ethyl Ester
CAS号:	338462-91-2
分子式:	C₂₀H₂₇NO₆
外观:	白色固体
分子量:	377.43
溶解性:	Ethyl Acetate
种类:	Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(5R)-5-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-phenylethyl]tetrahydro-2-oxo-3-furancarboxylic Acid Ethyl Ester is an intermediate in the synthesis of γ-Secretase Inhibitor, the enzyme complex that catalyzes the cleavage of the amyloid precursor protein (APP) to generate amyloid β-peptide (Aβ), the major causative agent in Alzheimer disease (AD).
参考文献	Chun, J., et al.: J. Org. Chem., 69, 7344 (2004); Nadin, A., et al.: Tetrahedron., 57, 1861 (2001);