产品编号：D470890

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	D470890
名称:	2,5-Dimethyl Celecoxib
别名:	4-[5-(2,5-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; DMC;
CAS号:	457639-26-8
分子式:	C₁₈H₁₆F₃N₃O₂S
外观:	Pale Brown to Light Brown Solid
熔点:	>138°C (dec.)
分子量:	395.4
储存:	冰箱保存
溶解性:	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A non-cyclooxygenase-2 inhibitor analog of Celecoxib (C251000). The celecoxib analog, 2,5-di-Me celecoxib (DMC), lacks COX-2 inhibitory activity but exhibits cytotoxic properties comparable to the COX-2 inhibitor Celecoxib.
参考文献	Deckmann, K. et al.: Biochem. Pharmacol., 80, 1365 (2010); Virrey, J.J. et al.: Mol. Cancer. Therap., 9, 631 (2010); Chen, S. et al.: Leukemia Res., 34, 250 (2010);

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