产品编号:D479400
产品规格:10mg
产品价格:面议
| 标准品编号: | D479400 |
| 名称: | 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin |
| 别名: | 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine rapamycin deriv. |
| CAS号: | 143030-02-8 |
| 分子式: | C₅₇H₉₃NO₁₃Si |
| 外观: | 白色固体 |
| 分子量: | 1028.43 |
| 储存: | -20°C Freezer |
| 溶解性: | Dichloromethane, Methanol |
| 种类: | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin is an intermediate in the synthesis of 8-O-Methyl-rapamycin which is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. |
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