42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin

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产品编号:D479400

产品规格:10mg

产品价格:面议


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标准品编号: D479400
名称: 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin
别名: 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine rapamycin deriv.
CAS号: 143030-02-8
分子式: C₅₇H₉₃NO₁₃Si
外观: 白色固体
分子量: 1028.43
储存: -20°C Freezer
溶解性: Dichloromethane, Methanol
种类: Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用: 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin is an intermediate in the synthesis of 8-O-Methyl-rapamycin which is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.
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