产品编号：D528800
产品规格：10mg
产品价格：面议
| 标准品编号: | D528800 |
| 名称: | Dolutegravir |
| 别名: | (4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide; GSK 1349572; S/GSK1349572; |
| CAS号: | 1051375-16-6 |
| 分子式: | C₂₀H₁₉F₂N₃O₅ |
| 外观: | 白色至淡黄色固体 |
| 熔点: | 187-189°C |
| 分子量: | 419.38 |
| 储存: | 冰箱保存 |
| 溶解度: | DMSO (Slightly, Sonicated, Heated), Methanol (Slightly, Heated) |
| 种类: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. |
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