产品编号：D528802
产品规格：1mg
产品价格：面议
| 标准品编号: | D528802 |
| 名称: | Dolutegravir-d4 |
| 别名: | (4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide-d4; GSK 1349572-d4; S/GSK1349572-d4; |
| 参考CAS: | 未标记：1051375-16-6 |
| 分子式: | C₂₀H₁₅D₄F₂N₃O₅ |
| 外观: | 灰白色至浅褐色固体 |
| 熔点: | 148-150°C (dec.) |
| 分子量: | 423.4 |
| 储存: | 冰箱保存 |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 种类: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Isotope labelled Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. |
| 参考文献 | |
