产品编号：D948560

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	D948560
名称:	1-(2,5-Dimethylphenyl)-4,4,4-trifluoro-1,3-butanedione
CAS号:	94856-19-6
分子式:	C₁₂H₁₁F₃O₂
分子量:	244.21
种类:	Building Blocks; Miscellaneous;
应用:	1-(2,5-Dimethylphenyl)-4,4,4-trifluoro-1,3-butanedione is an intermediate in the synthesis of 2,5-Dimethyl Celecoxib (D470890), which is a non-cyclooxygenase-2 inhibitor analog of Celecoxib (C251000). The celecoxib analog, 2,5-di-Me celecoxib (DMC), lacks COX-2 inhibitory activity but exhibits cytotoxic properties comparable to the COX-2 inhibitor Celecoxib.
参考文献	Deckmann, K. et al.: Biochem. Pharmacol., 80, 1365 (2010); Virrey, J.J. et al.: Mol. Cancer. Therap., 9, 631 (2010); Chen, S. et al.: Leukemia Res., 34, 250 (2010);