产品编号：D955400

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	D955400
名称:	N- Didesmethyl Bedaquiline
别名:	R 207910d; (αS,βR)-α-(2-Aminoethyl)-6-bromo-2-methoxy-α-1-naphthalenyl-β-phenyl-3-quinolineethanol; (1R,2S)-4-Amino-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol
CAS号:	955404-04-3
分子式:	C₃₀H₂₇BrN₂O₂
分子量:	527.45
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N- Didesmethyl Bedaquiline is a metabolite of Bedaquiline (B119540). (αS,βR)-Bedaquiline is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
参考文献	Cuyckens, Filip, et al.: Anal. Bioanal. Chem.,390, 1717(2008); Cheepsattayakorn, A., et al.: Anti-Infect. Drug. Discover.,7, 141 (2012); de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009)