产品编号：E588990
产品规格：1mg
产品价格：面议
| 标准品编号: | E588990 |
| 名称: | Epothilone B (synthetic) |
| 别名: | (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione; (-)-Epothilone B; EPO 906; EPO 906A; Epothilone B; Patupilone; |
| CAS号: | 152044-54-7 |
| 分子式: | C₂₇H₄₁NO₆S |
| 外观: | 白色固体 |
| 熔点: | 95-97°C |
| 分子量: | 507.68 |
| 储存: | -20°C Freezer, Under Inert Atmosphere |
| 溶解度: | Chloroform, Dichloromethane, DMSO, Ethanol, Methanol |
| 种类: | Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone B is what is known as a microtubule stabilizer. When a cell divides, the chromosomes that will end up in each cell are separated by thin filaments called microtubules. Normally these microtubules then break down as the cell division progresses. This class of cytotoxic chemo drugs prevents that break down and thus prevents cells from completing division. |
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