产品编号：E951870

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	E951870
名称:	O-Desaminoethoxy O-2-(tert-Butoxy)-2-oxoethoxy Dehydroamlodipine
别名:	3-Ethyl 5-Methyl 2-((2-(tert-Butoxy)-2-oxoethoxy)methyl)-4-(2-chlorophenyl)-6-methylpyridine-3,5-dicarboxylate
分子式:	C₂₄H₂₈ClNO₇
分子量:	477.93
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	O-Desaminoethoxy O-2-(tert-Butoxy)-2-oxoethoxy Dehydroamlodipine is an intermediate for the synthesis of O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine (D289480), which is the metablolite of Amlodipine (A633495), a long-acting calcium channel blocker that is commonly used as an anti-hypertensive in the treatment of cardiovascular conditions.
参考文献	Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986), Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987), Haria, M., et al.: Drugs, 50, 560 (1995)